Description

Overview

Hydrocodone 10/325mg is a prescription painkiller combining hydrocodone (10mg), an opioid analgesic, with acetaminophen (325mg), a non-opioid pain reliever. It is used for moderate to severe pain that cannot be managed with over-the-counter medication, such as post-surgical pain, injury-related pain, or chronic conditions.

Uses

Hydrocodone 10/325mg is prescribed for:

• Postoperative pain
• Pain from injuries (fractures, severe sprains)
• Chronic pain (arthritis, back pain)
• Cancer-related pain

Not recommended for:

• Mild or temporary pain

Composition

• Active Ingredients: Hydrocodone 10mg, Acetaminophen 325mg
• Drug Class: Opioid analgesic / Combination pain reliever

Dosage & Administration

• Typically taken orally every 4–6 hours as needed
• Maximum 6 tablets per day (unless instructed by doctor)
• Swallow whole; do not crush or chew
• Take with food or milk to reduce stomach upset

How It Works

Hydrocodone binds to opioid receptors in the brain and spinal cord to block pain signals. Acetaminophen enhances pain relief by increasing the pain threshold and reducing fever or inflammation.

Precautions & Safety

• Inform your doctor if you have liver/kidney problems, respiratory disorders, or a history of substance abuse
• Avoid alcohol, sedatives, and machinery operation
• Use caution in elderly patients or those with chronic health conditions

Common Side Effects

• Drowsiness or sedation
• Dizziness
• Nausea or vomiting
• Constipation
• Dry mouth
• Mild itching or rash

Serious Risks & Warnings

• Addiction and dependence
• Respiratory depression
• Overdose risk, especially with alcohol or other sedatives
• Liver damage from excessive acetaminophen
• Severe allergic reactions

Drug Interactions

• Other opioids or sedatives
• Benzodiazepines
• Alcohol
• Sleep aids or muscle relaxants
• Certain antidepressants or antipsychotics

Addiction and Withdrawal

Hydrocodone 10/325mg has abuse potential and can cause dependence. Withdrawal symptoms include restlessness, insomnia, nausea, and muscle pain. Always taper under medical supervision.

Conclusion

Hydrocodone 10/325mg provides strong pain relief for moderate to severe pain. It should only be used as prescribed, under medical supervision, to minimize the risks of addiction, overdose, or liver damage.

Delivery options

Click & Collect

£1.50 or free if you spend £15 or more from your choice of 1,800 stores.

Standard Delivery

£3.95 or free when you spend £25 or more.

Next Day Delivery

Order by 10pm (subject to change during promotions), available 7 days a week for £5.95. This may not be available during public holidays or weekends in between public holidays. To be eligible for Next Day Delivery, Pharmacy Medicines must be ordered by 8pm.

Airport Click & Collect

£4.50 - Select a delivery date 3 days before your flight.

Named Day Delivery

£5.75 - choose a weekday within the next 14 days for delivery. Subject to availability.

For more information see our delivery help or view our returns policy.