Description

Overview

Oxycodone 80mg is a prescription opioid analgesic designed for severe, chronic pain management in patients who require continuous, long-term opioid therapy. This high-strength extended-release formulation contains oxycodone hydrochloride and is not intended for as-needed use. It provides around-the-clock pain relief for conditions such as cancer pain, post-surgical recovery, or major trauma.

Uses

Oxycodone 80mg is prescribed for:

• Severe pain not controlled by lower-dose painkillers
• Chronic pain requiring continuous, 24/7 management
• Cancer-related pain or advanced arthritis
• Post-surgical pain where other medications are ineffective

Not recommended for:

• Opioid-naïve patients
• Short-term or minor pain episodes

Composition

• Active Ingredient: Oxycodone Hydrochloride 80mg
• Drug Class: Opioid analgesic / Narcotic

Dosage & Administration

• Typical adult dosage: 1 tablet every 12 hours
• Take with water; do not crush, chew, or split tablets
• Onset: 20–30 minutes (pain relief builds gradually due to ER formulation)
• Duration: Up to 12 hours
• Important: Use only as prescribed. Overdose can be fatal.

How It Works

Oxycodone binds to mu-opioid receptors in the brain and spinal cord, blocking pain signals and altering the perception of pain. The extended-release tablet provides long-lasting, stable blood levels for consistent pain relief.

Precautions & Safety

• Inform your doctor if you have: respiratory issues, liver/kidney disease, history of substance abuse, or mental health conditions
• Avoid alcohol, sedatives, and operating machinery while on Oxycodone
• Elderly patients and those with co-morbidities require special caution

Common Side Effects

• Nausea or vomiting
• Constipation
• Drowsiness or sedation
• Dizziness or lightheadedness
• Dry mouth
• Itching or sweating

Serious Risks & Warnings

• High potential for addiction, dependence, and abuse
• Respiratory depression (can be life-threatening)
• Overdose risk, especially with alcohol or sedatives
• Withdrawal symptoms if stopped abruptly
• Tolerance and dependence with long-term use

Drug Interactions

Oxycodone 80mg may interact with:

• Other opioids
• Benzodiazepines (Xanax, Valium)
• Sedatives or sleep aids
• Alcohol
• Muscle relaxants or certain antidepressants

Addiction and Withdrawal

Oxycodone has a high potential for abuse. Dependence can occur even at prescribed doses. Withdrawal symptoms include restlessness, sweating, insomnia, nausea, and muscle aches. Always taper under medical supervision.

Conclusion

Oxycodone 80mg is a potent, long-lasting opioid for patients with severe, chronic pain. It should only be used under strict medical supervision by patients already tolerant to opioids. When taken responsibly, it can significantly improve comfort and quality of life for those with intractable pain.

Delivery options

Click & Collect

£1.50 or free if you spend £15 or more from your choice of 1,800 stores.

Standard Delivery

£3.95 or free when you spend £25 or more.

Next Day Delivery

Order by 10pm (subject to change during promotions), available 7 days a week for £5.95. This may not be available during public holidays or weekends in between public holidays. To be eligible for Next Day Delivery, Pharmacy Medicines must be ordered by 8pm.

Airport Click & Collect

£4.50 - Select a delivery date 3 days before your flight.

Named Day Delivery

£5.75 - choose a weekday within the next 14 days for delivery. Subject to availability.

For more information see our delivery help or view our returns policy.